rodrigo de jerez, el primer, español que vio fumar y adoptar el vicio.aquel español que cuando regreso de su viaje con colon fue descubierto fumando solo, en un cuarto de atras de su casa . "Y un dia su mujer entró de improviso y lo vio echando humo po todos los orificios de su cara...su mujer lo acuso ante la inquisicion de tener pacto con el diablo, y aquel primer fumador, en la hoguera, se convirtio en humo. "
Alzheimer's disease (AD) has become a growing problem in the medical, psychiatric, neurological, epidemiological, social and economic order, particularly in countries with a high life expectancy Alzheimer's dementia can be classified according to the age of onset in presenile or early onset, which appears before age 65 and senile or late onset, ie onset after age 65. It according to the presence or absence of a family history of the disease is classified into familial AD and sporadic AD, respectively. However, these classifications are not mutually exclusive. The development achieved by genetic has demonstrated the involvement of several chromosomes in the development of the disease. Chromosomes 1, 14 and 21 are associated with familial forms of start precoz. While late onset forms appear linked to chromosomes 12 and 19 In this paper we delved into the study of chromosome 21 and the amyloid beta protein , because there are many findings that relate to deposit excess am...
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