en las parsonas que padecen de tabaquismo y alcohol, estss se comportan como una anafilaxia; una especie de reaccion alergica. con el tabaco, se van a producir cambios de epitelios a nivel bronquial, conservandoce las celulas caliciformes productoras de mucus.a nivel del ojo cambios en la calidad del cristalino y esclerotica bulbar, daños a en los vasos arteriales y venosos. in people who suffer from smoking and alcohol use, these behave as anaphylaxis, a kind of allergic reaction. with snuff, changes will occur at bronchial epithelia, conserving itself producing goblet cells mucus.a eye level changes in the quality of the lens and sclera bulbar damage in arterial and venous vessels 在遭受吸煙和酗酒的人，這些表現為過敏性反應，是一種過敏性反應。鼻煙的變化將發生在支氣管上皮細胞，節約生產杯狀細胞本身mucus.a眼水平變化的鏡頭質量和鞏膜延髓損傷動脈和靜脈血管。
Substance P is the first neuroactive substance that is proposed as a neurotransmitter. As for the pharmacological properties of substance P, they were demonstrated to check exhibiting potent hypotensive properties that were not blocked by atropine. He was later identified as the first active neuropeptide and was proposed as a neurotransmitter. In the 70s the structure is now known to contain eleven amino acids, of which six corresponding to the C-terminus are essential for its biological activity was determined. Substance P (SP) is a neuropeptide of eleven amino acids, are much smaller than other neurotransmitters amounts, is synthesized in the cell body and transported along the axon to the terminals, it is synthesized as part of a prepropeptide ( preproteins or precursors) of higher molecular weight which then moves to the cisterns of the endoplasmic reticulum, where it is disintegrated to produce a proprotein. The proprotein is transported to the Golgi apparatus, where they may fac...
Comentarios