Lysophosphatidic acid (LPA; acyl-glycerol-3-phosphate) is a phospholipid growth factor exerts That diverse biological effects in cellular and organ systems. LPA exhibits multiple physiological activities through the activation of LPA receptors (LPA1-6) Which are G-protein coupled receptors (GPCRs) That act through various downstream signal transduction pathways. LPAs are produced from lysophosphatidylcholine by autotaxin (ATX) (Also known as lysophospholipase D, in the blood
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